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Ashleigh R Poh Selected Research

Proto-Oncogene Proteins c-hck

6/2022Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy.
1/2020Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice.
10/2017Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression.
6/2015Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells.

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Ashleigh R Poh Research Topics

Disease

10Neoplasms (Cancer)
06/2022 - 09/2014
3Colonic Neoplasms (Colon Cancer)
01/2019 - 09/2014
2Carcinogenesis
01/2020 - 09/2014
2Stomach Neoplasms (Stomach Cancer)
01/2019 - 07/2016
1Malignant Mesothelioma
05/2021
1Osteoporosis
01/2019
1Gastrointestinal Neoplasms (Gastrointestinal Cancer)
01/2019
1Intestinal Neoplasms (Intestinal Cancer)
01/2019
1Hematologic Neoplasms (Hematological Malignancy)
10/2017
1Leukemia
06/2015
1Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
09/2014
1Inflammation (Inflammations)
05/2014

Drug/Important Bio-Agent (IBA)

5CytokinesIBA
01/2019 - 09/2014
4Proto-Oncogene Proteins c-hckIBA
06/2022 - 06/2015
3src-Family KinasesIBA
06/2022 - 10/2017
2STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2020 - 09/2014
2InterleukinsIBA
01/2019 - 01/2019
2Interleukin-6 (Interleukin 6)IBA
01/2019 - 01/2019
2CateninsIBA
01/2019 - 09/2014
2Interleukin-33IBA
01/2019 - 05/2014
2Interleukin-11 (Interleukin 11)IBA
01/2019 - 01/2019
2Phosphotransferases (Kinase)IBA
06/2015 - 09/2014
1Programmed Cell Death 1 ReceptorIBA
06/2022
1AZD5991IBA
05/2021
1AZD0466IBA
05/2021
1AZD4320IBA
05/2021
1Pemetrexed (MTA)FDA Link
05/2021
1Cisplatin (Platino)FDA LinkGeneric
05/2021
1Lysine (L-Lysine)FDA Link
05/2021
1Dendrimers (Dendrons)IBA
05/2021
1MucinsIBA
01/2020
1bazedoxifeneIBA
01/2019
1Selective Estrogen Receptor Modulators (SERM)IBA
01/2019
1AlarminsIBA
01/2019
1SteroidsIBA
01/2019
1Complement System Proteins (Complement)IBA
01/2018
1Biomarkers (Surrogate Marker)IBA
01/2018
1Biological ProductsIBA
07/2016
1Proteins (Proteins, Gene)FDA Link
06/2015
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
06/2015
1tyrosine receptor (receptor, tyrosine)IBA
06/2015
1Janus KinasesIBA
09/2014
1Type I Tumor Necrosis Factor ReceptorsIBA
05/2014

Therapy/Procedure

3Therapeutics
01/2018 - 07/2016
1Immunotherapy
06/2022
1Drug Therapy (Chemotherapy)
05/2021